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DIM-plus™ contains diindolylmethane, a phytonutrient found in cruciferous vegetables including broccoli, Brussels sprouts, cabbage, cauliflower and kale. Diindolylmethane has unique benefits that support the activity of enzymes that improve estrogen metabolism.* Research shows diindolylmethane increases the level of "favorable" estrogens (2-hydroxyestrogen) while reducing the level of "less favorable" estrogens (16-hydroxyestrogen).*